Political and Socioeconomic
Perspectives
Dr. Jean Vivien Mombouli

About Dr. Jean Vivien Mombouli

Jean Vivien Mombouli, PhD
Directeur du Departement de la Recherche et de la Production
Laboratoire Nationale de Sante Publique
Brazzaville, Republic of Congo

Dr. Jean-Vivien Mombouli is Director of the Department of Research and Production, National Laboratory for Public Health of Congo and Assistant Professor at Marien Ngouabi University of Brazzaville, Congo. Dr. Mombouli received his PhD in Molecular Physiology and Pharmacology from the University of Poiters, France. He has written over 22 original research articles and 6 book chapters.

Dr. Mombouli’s present aim of study is the pathophysiological modulation of blood vessel function induced by infectious agents in Malaria, HIV-AIDS, Human African Trypanosomiasis, Schistosomiasis and Ebola virus. Blood borne microbial pathogens cause pro-inflammatory reactions that impact negatively the perfusion of organs with nutritious elements and/or tissue cleansing by blood of metabolism by-products. The resulting impairment of blood flow causes some stress that may contribute to observed morbidity, and in some instances to death.

Blood borne pathogens alter blood vessel function (control of vessel caliber and blood fluidity) in ways that support our overall working hypothesis that certain drugs developed for cardiovascular diseases may be of great help in the adjuvant symptomatic treatment of severe infectious diseases. Scientific literature supports in theory such a role for cardiovascular drugs in the treatment of Ebola Hemorrhagic fever and malaria.

The National Public Health Laboratory aims to establish a map of health risks that would cover the Republic of Congo. Construction of both resident and mobile laboratory capacity to be able to monitor routinely emergence of acute disease outbreaks such as Ebola viral epidemics, or assess parametric changes in perennial epidemics such as malaria parasite drug-resistance patterns.

To these ends, cooperation in remote areas with community-based organizations such as the Congolese Red Cross or conservation organizations is warranted to compensate for lack of personnel.